Clin2
NCT06218810Possibly a fitRecruiting

Combination therapy for advanced MSS, RAS-mutated colorectal cancer

Metastatic Colorectal CancerMicrosatellite Stable Colorectal CarcinomaRAS MutationCadonilimab

Part of Cancer, Digestive system clinical trials.

This trial tests a new combination of three medicines for people with a certain type of advanced colorectal cancer that has not been treated before. It aims to see if adding an immunotherapy drug (Cadonilimab) to standard chemotherapy and a targeted therapy (Bevacizumab) can help shrink tumors and delay disease progression.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
53 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are 18 to 75 years old
  • You have advanced colorectal cancer that has spread and cannot be removed by surgery
  • Your tumor is MSS-type and has a RAS mutation
  • You have not received any prior cancer treatment for this advanced stage
  • You have at least one tumor that can be measured on scans and has not been treated with radiation
  • You do not have an active autoimmune disease that requires treatment

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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