Testing NPX887 for advanced solid tumors with B7-H7 protein
Part of Cancer clinical trials.
This trial tests a new drug called NPX887 that targets a protein (B7-H7) on certain cancer cells to help your immune system fight them. It is for people with advanced solid tumors that have not responded to other treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a type of solid tumor cancer (like lung, kidney, colorectal, stomach, bile duct, or ovarian) that has spread or come back after standard treatments stopped working.
- Your tumor must have a protein called B7-H7 (HHLA2) on its surface. This can be checked on a stored tumor sample.
- You are able to get around and take care of yourself (ECOG score 0-2).
- You haven't had cancer treatment (chemo, targeted therapy, or radiation) in the last 1-2 weeks, and any side effects from prior treatments have mostly resolved.
- You do not have active or growing brain metastases, and you have not had severe lung or colon inflammation from prior immunotherapy.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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