Clin2
NCT06242509Possibly a fitRecruiting

Akkermansia bacteria in prostate cancer

Metastatic Castration-resistant Prostate Cancer

Treatments studied

Part of Cancer clinical trials.

This trial looks at whether a specific gut bacterium, Akkermansia muciniphila, is linked to how well hormone therapy works in men with advanced prostate cancer that no longer responds to standard hormone treatment. You may join if you are about to start a new type of hormone therapy.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
52 people
Ages
18 years to 100 years
Study type
Observational

Who can take part

  • You are 18 years or older.
  • You have advanced prostate cancer that has spread and is no longer controlled by standard hormone therapy.
  • You have a testosterone level below 50 ng/dL (castrate level).
  • You are about to start a next-generation hormone therapy (like abiraterone) within 15 days of joining.
  • You are willing to follow the study schedule and procedures.
  • You are covered by French social security.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06492122Recruiting· Phase 1
Study of a radioactive drug for advanced prostate cancer

This trial tests a new radioactive treatment, [225Ac]Ac-FL-020, for men with metastatic castration-resistant prostate cancer (mCRPC) that has gotten worse despite other treatments. It's for those who have had at least one prior hormone therapy or chemotherapy.

Duarte, California
NCT06629779Recruiting· Phase 3
Study of Mevrometostat for Advanced Prostate Cancer

This study tests a new drug called mevrometostat for men with a specific type of advanced prostate cancer that has spread and is still growing despite hormone therapy. It aims to see if the drug can help control the cancer.

Chandler, Arizona
NCT05125016Recruiting· Phase 1/Phase 2
Study drug for advanced prostate cancer after standard treatments

This early-phase study tests whether REGN4336 is safe and how well it works, by itself or with REGN5678, in adults with advanced prostate cancer. It may help people whose cancer has continued to worsen despite standard prostate cancer medicines.

Palo Alto, California
NCT06616597Recruiting· Phase 2
Targeting gut bacteria to help prostate cancer treatment work again

This trial tests whether adding metronidazole, an antibiotic, can make abiraterone work better in men with metastatic prostate cancer whose PSA is rising despite treatment. It aims to target gut bacteria that may be fueling resistance to the therapy.

Baltimore, Maryland
NCT05802121Recruiting· Early Phase 1
Testing a gut bacteria supplement side effects during prostate hormone therapy

This early-phase study looks at how changing gut bacteria (especially Akkermansia) affects metabolic side effects in men starting prostate hormone therapy (ADT). It may help researchers understand how to reduce or manage side effects for people on ADT.

London, Ontario
NCT06423976Recruiting
Studying microbes in prostate cancer tumors

This trial collects tumor samples from men with prostate cancer to study the bacteria and other microbes inside the tumor. It aims to learn how these microbes might affect the cancer and treatment.

Sutton, Surrey

Hear when a new Metastatic Castration-resistant Prostate Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.