Clin2
NCT06248996Possibly a fitRecruiting

Testing a stronger radiation schedule for large head and neck cancers

Head and Neck Squamous Cell Carcinoma

Treatments studied

Part of Cancer clinical trials.

This trial tests whether giving a slightly different schedule of radiation (more frequent, smaller doses) can improve treatment for people with large head and neck cancers. It is for patients who are getting radiation as their main treatment, sometimes with chemotherapy as well.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
308 people
Ages
18 years to 100 years
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have a new, untreated head and neck cancer (oropharynx, hypopharynx, larynx, or oral cavity) that has not spread to other parts of the body, and your doctor plans to treat it with radiation (with or without chemo) to try to cure it.
  • Your tumor must be large enough: for p16-positive oropharynx cancers, at least the size of a walnut; for others, at least the size of a large walnut.
  • You have not had any prior radiation to the head or neck, and you have no other active cancers (except certain minor skin cancers or cancers that have been cured for at least 3 years).
  • You are in generally good health (able to walk and care for yourself with little help) and can understand the treatment plan to give your consent.
  • You are not pregnant or breastfeeding, and you have no serious medical condition that would limit your life expectancy to less than 3 years.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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