Clin2
NCT06252142Possibly a fitRecruiting

Monitoring after rectal cancer treatment

Rectal Neoplasms

Part of Cancer, Digestive system clinical trials.

This study looks at whether careful monitoring (watch and wait) is a good option for people with rectal cancer who have already had certain treatments. It aims to see if this approach can help avoid major surgery.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
260 people
Ages
18 years to 90 years
Study type
Observational

Who can take part

  • You are 18 years or older.
  • You have a type of rectal cancer called adenocarcinoma (not the signet or mucinous types).
  • Your cancer is locally advanced (T1-4a or N0-2) and has spread to a limited number of other places (1 to 2 organs, or 1 to 2 spots in one organ).
  • Your tumor is not completely around the bowel and is less than 7 cm long.
  • Your tumor is in the lower to mid rectum, up to 7 cm from the anal opening.
  • You have already completed a specific set of treatments aimed at a watch and wait approach, including chemotherapy and radiation (with or without brachytherapy), by March 2024.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT03125343Recruiting
Watch-and-wait after rectal cancer treatment for select patients

This study looks at whether some people with rectal cancer can safely avoid immediate surgery after (chemo)radiation, instead closely monitoring their response. It may help some patients reduce treatment burden if the cancer fully responds.

Gothenburg
NCT03179540Recruiting
Watch-and-wait treatment after rectal cancer radiation

This trial looks at a “non-surgery” approach for some people with locally advanced rectal cancer who respond very well to radiation plus chemotherapy. If your cancer shows a complete clinical response on follow-up checks, the study may help you avoid an immediate major operation while closely monitoring you.

Toronto, Ontario
NCT06631443Recruiting
Asian Watch-and-Wait Study for Rectal Cancer

This study is for people with rectal cancer who have had treatment like radiation or chemo and their tumor has disappeared or nearly disappeared. Instead of surgery right away, doctors will closely monitor the cancer with regular check-ups to make sure it stays gone.

Mumbai, Maharashtra
NCT07669298Recruiting
Monitoring vs chemoradiation for early rectal cancer

This study compares two approaches after early-stage rectal cancer is removed: either careful monitoring or a follow-up treatment with chemotherapy and radiation. The goal is to see which strategy works better to keep the cancer from returning.

Limoges
NCT04443543Not yet recruiting· Phase 2
Watch-and-wait after chemoradiation for rectal cancer

This study looks at whether some people with locally advanced rectal cancer can safely delay or avoid surgery after chemoradiation by closely monitoring tumors (“watch and wait”). It may help those who strongly want to preserve the anus, but only if they meet strict safety checks.

Shanghai, Shanghai Municipality
NCT03594630Recruiting· Early Phase 1
Watchful waiting then chemotherapy before surgery for rectal cancer

This trial studies whether a period of active surveillance (watching closely) and chemotherapy before surgery can improve outcomes for people with stage II–III rectal cancer. You would also receive standard chemo-radiation if you qualify, then proceed to surgery.

Houston, Texas

Hear when a new Rectal Neoplasms trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.