Clin2
NCT06631443Possibly a fitRecruiting

Asian Watch-and-Wait Study for Rectal Cancer

Rectal AdenocarcinomaRectal Cancer

Part of Cancer, Digestive system clinical trials.

This study is for people with rectal cancer who have had treatment like radiation or chemo and their tumor has disappeared or nearly disappeared. Instead of surgery right away, doctors will closely monitor the cancer with regular check-ups to make sure it stays gone.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
337 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You have been diagnosed with rectal cancer (adenocarcinoma).
  • You are 18 years or older.
  • Your cancer had not spread to other parts of the body at diagnosis.
  • You have completed radiation or chemotherapy before any surgery.
  • Your tumor has shrunk significantly or disappeared after treatment.
  • You are willing to have regular check-ups instead of immediate surgery.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04443543Not yet recruiting· Phase 2
Watch-and-wait after chemoradiation for rectal cancer

This study looks at whether some people with locally advanced rectal cancer can safely delay or avoid surgery after chemoradiation by closely monitoring tumors (“watch and wait”). It may help those who strongly want to preserve the anus, but only if they meet strict safety checks.

Shanghai, Shanghai Municipality
NCT03594630Recruiting· Early Phase 1
Watchful waiting then chemotherapy before surgery for rectal cancer

This trial studies whether a period of active surveillance (watching closely) and chemotherapy before surgery can improve outcomes for people with stage II–III rectal cancer. You would also receive standard chemo-radiation if you qualify, then proceed to surgery.

Houston, Texas
NCT05000697Recruiting
Watch-and-wait or chemo after rectal cancer radiation

This trial studies people with early-to-mid stage distal rectal cancer who may get radiation and chemotherapy, with an option that may include an extra drug (oxaliplatin). It also tests whether some people can safely follow a “watch and wait” plan instead of immediate additional treatment, aiming to reduce overtreatment while keeping cancer control.

Buenos Aires
NCT07669298Recruiting
Monitoring vs chemoradiation for early rectal cancer

This study compares two approaches after early-stage rectal cancer is removed: either careful monitoring or a follow-up treatment with chemotherapy and radiation. The goal is to see which strategy works better to keep the cancer from returning.

Limoges
NCT04643041Recruiting
Watch-and-wait after PD-1 for certain rectal cancer

This study looks at whether people with a very strong response to a PD-1 antibody can safely delay or avoid more standard rectal cancer treatment (a “watch-and-wait” approach). It may help some people avoid surgery, radiation, or ongoing treatment while still closely monitoring the cancer.

Guangzhou, Guangdong
NCT06637462Recruiting
Studying standard treatment response before rectal cancer surgery

This study looks at how rectal cancer responds to the usual chemotherapy and radiation given before surgery. It aims to learn if certain molecular features of your tumor can predict how well it responds to treatment.

Middletown, New Jersey

Hear when a new Rectal Adenocarcinoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.