Watch-and-wait treatment after rectal cancer radiation
Part of Cancer, Digestive system clinical trials.
This trial looks at a “non-surgery” approach for some people with locally advanced rectal cancer who respond very well to radiation plus chemotherapy. If your cancer shows a complete clinical response on follow-up checks, the study may help you avoid an immediate major operation while closely monitoring you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re 18 or older and can sign written consent
- You already completed standard radiation plus chemo for rectal cancer (about 50 Gy with 5-FU or capecitabine)
- Your rectal cancer stage fits Stage II–III and is in a locally advanced (not spread) category
- Between 8 and 10 weeks after treatment, doctors find signs of a complete clinical response on exams/tests
- You can have MRI scans, and you are likely a surgical candidate if needed (able to undergo surgery)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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