Testing a new blood filter for sepsis patients with weakened immune systems
Part of Infections clinical trials.
This trial tests a new blood-cleansing device (HemoSystem REBOOT) that may help people with sepsis by removing harmful substances and improving immune function. It is for critically ill patients whose immune systems remain suppressed despite standard sepsis treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You are in the intensive care unit (ICU) or intermediate care unit with a stay expected longer than 48 hours
- You have a confirmed or strongly suspected bacterial infection causing sepsis with dangerously low blood pressure that needs medication, and high lactate levels
- Your immune system is still weakened, measured by a blood test marker (mHLA-DR) taken at least twice, 20 to 72 hours apart
- You are not on long-term immune-suppressing medicines (except low-dose hydrocortisone for sepsis) and do not have a pre-existing severe immune condition or active cancer
- You do not have uncontrolled bleeding, low platelet count, very low body weight, or known allergies to the device components
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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