Long-term follow-up of methotrexate for hand osteoarthritis
Treatments studied
Part of Bones, joints & muscles, Immune system & allergy clinical trials.
This study follows up on people who took part in the MERINO trial to see if methotrexate has lasting benefits for hand osteoarthritis. It aims to understand how the drug affects pain and joint health over 30 months.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You were part of the MERINO trial for hand osteoarthritis.
- You had finger joint pain that did not improve enough with common pain relievers like paracetamol or NSAIDs.
- You had hand pain or stiffness on most days for at least 6 weeks before joining the MERINO trial.
- You had hand osteoarthritis confirmed by a doctor, with specific joint damage on x-rays and signs of inflammation on ultrasound.
- You do not have any condition that makes methotrexate unsafe for you, such as kidney, liver, or lung problems, certain infections, or pregnancy.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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