Methotrexate for hand osteoarthritis not helped by usual treatments
Treatments studied
Part of Bones, joints & muscles, Pain clinical trials.
This trial tests if methotrexate, a medicine that reduces inflammation, can ease pain and improve function in people with hand osteoarthritis that hasn't gotten better with standard treatments like pain relievers or hand therapy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have hand osteoarthritis (confirmed by X-ray within the last 3 months showing at least 3 affected finger joints) and symptoms have lasted more than 3 months.
- You are not pregnant or breastfeeding, and you are not using certain medications like high-dose aspirin, Bactrim, morphine, or corticosteroids.
- You do not have psoriasis, inflammatory arthritis, gout, or other joint conditions.
- You do not have severe kidney or liver problems, active infections (like tuberculosis or hepatitis), or a weakened immune system.
- You have not had hyaluronic acid injections in your hands in the last 6 months or cortisone injections in the last 3 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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