Study of immune therapy injections for advanced melanoma
Treatments studied
Part of Cancer, Skin clinical trials.
This trial tests whether injecting immune-boosting drugs directly into melanoma tumors, alongside the immunotherapy pembrolizumab, can help people whose cancer has not responded to previous immunotherapy. It aims to shrink tumors and improve treatment outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have advanced melanoma (stage III or IV) that cannot be removed with surgery.
- Your melanoma has grown or not responded to previous treatment with an anti-PD-1/PD-L1 immunotherapy (like pembrolizumab or nivolumab).
- You have at least one tumor that can be injected directly (under the skin or in a lymph node).
- You are generally well enough to carry out daily activities (ECOG performance status 0 or 1).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This trial tests a treatment made from your own immune cells (called tumor-infiltrating lymphocytes). The cells are taken from a tumor sample, multiplied in a lab, and given back to you to help fight the cancer. It's for people with melanoma that has not responded to standard immunotherapy.
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