Pressurized chemotherapy and surgery for high-risk stomach cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests a new way to give chemotherapy directly into the abdomen during surgery for stomach cancer that has a high risk of coming back. It may help reduce the chance of the cancer returning.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have stomach cancer or cancer at the junction of the stomach and food pipe (Siewert type III).
- Your cancer is at a certain stage (T3-4a, or T2 if it is poorly differentiated, or any stage if cancer cells were found in abdominal fluid but cleared after chemotherapy).
- You are between 18 and 80 years old.
- You are fit enough for daily activities (ECOG 0-1).
- You are scheduled to have minimally invasive surgery to remove the stomach (robotic or laparoscopic gastrectomy).
- You do not have severe kidney, heart, or liver problems, and you are not allergic to the chemotherapy drugs used.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests giving chemotherapy through a vein and directly into the belly before surgery for advanced stomach cancer. The goal is to shrink the cancer and see if this approach improves outcomes.
This trial tests whether adding heated chemotherapy to the belly right after surgery can help people with stomach cancer live longer. It is done during the same operation, aiming to kill any remaining cancer cells.
This trial looks at a way to give chemotherapy into the abdomen (through a small tube during laparoscopy) for certain stomach cancers. It aims to see whether this approach improves cancer control and surgical outcomes for people whose tumors can potentially be removed.
This trial tests a treatment called HIPEC (heated chemotherapy given directly into the abdomen during surgery) for stomach cancer that has spread to the lining of the belly. The goal is to see if this approach can help remove or shrink the cancer and improve outcomes.
This trial tests a minimally invasive surgery for stomach cancer that has spread to lymph nodes near the main blood vessels (para-aortic area). The surgery is done after a combination of chemotherapy and immunotherapy to shrink the tumor. It aims to see if this approach is safe and effective.
This study tests whether a thorough surgery to remove stomach cancer in the abdomen, followed by chemotherapy given through the belly and by vein, can improve outcomes. It’s for people newly diagnosed with stomach cancer that has limited spread to the belly lining.
Hear when a new Gastric Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.