Protecting the heart with dapagliflozin during breast cancer treatment
Treatments studied
Part of Cancer, Heart & circulation, Skin clinical trials.
This trial tests if the diabetes drug dapagliflozin can protect the heart in people with breast cancer receiving a type of chemotherapy called anthracyclines. You may be able to join if you are between 18 and 80, have stage I-III breast cancer, and are about to start anthracycline treatment within the next 60 days.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 79 years old.
- You have been diagnosed with stage I, II, or III breast cancer and are scheduled to start anthracycline chemotherapy within the next two months.
- You do not have known heart failure, severe heart valve disease, a history of stroke, or certain heart rhythm problems like atrial fibrillation.
- You do not have diabetes or a recent blood sugar level that suggests diabetes.
- You are not pregnant, breastfeeding, and if you could become pregnant, you agree to use highly effective birth control.
- Your kidney function and liver tests meet study thresholds, and you have no active serious infections like HIV or hepatitis.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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