Clin2
NCT06314997Possibly a fitRecruiting

Tracking cancer cells during chemo

Objective Responsive Rate (ORR)

Treatments studied

Part of Cancer clinical trials.

This trial studies how proteins on circulating tumor cells change during chemotherapy in people with colorectal cancer that has spread.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
150 people
Ages
18 years to 100 years
Study type
Interventional

Who can take part

  • You are able to get up and care for yourself (ECOG score 0-2)
  • Your doctor says you are healthy enough for chemotherapy
  • You do not have an active infection before starting the trial
  • You have not had another cancer in the last 3 years (except some skin cancers)
  • You do not have a second colorectal cancer that started at the same time

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07558083Recruiting· Phase 3
Tracking colorectal cancer response using blood tests

This study tests whether a simple blood test can track how well your colorectal cancer is responding to first-line chemotherapy. By monitoring cancer markers in your blood, doctors may be able to detect treatment changes earlier than traditional imaging.

Mechelen, Antwerpen
NCT07094893Not yet recruiting· Phase 4
Anti-EGFR drugs for right-sided advanced colorectal cancer

This trial tests whether adding an anti-EGFR drug to standard chemotherapy helps people with right-sided advanced colorectal cancer that has not had chemotherapy before. You need to have a specific gene pattern (no RAS mutation and high AREG/EREG) to join.

NCT07318389Not yet recruiting· Early Phase 1
Profiling treatment resistance in metastatic colorectal cancer

This trial studies tumor samples from people with metastatic colorectal cancer to understand why treatments stop working. It aims to find new ways to target cancer that has become resistant.

Houston, Texas
NCT06907342Recruiting· Phase 2
Personalized chemo selection for advanced colorectal cancer

This trial tests whether a functional test on a tumor biopsy can help choose the best first chemotherapy regimen (FOLFOX or FOLFIRI) for people with metastatic colorectal cancer. It aims to improve outcomes by matching treatment to each person's unique tumor biology.

Trondheim
NCT05038358Recruiting
Study of immune and chemo resistance in colorectal tumors

This study looks at how the immune system around a colorectal tumor relates to resistance to chemotherapy. You may be able to join if you are having surgery soon for colorectal cancer and have not yet had chemotherapy before surgery.

Grenoble
NCT05315700Recruiting· Phase 1/Phase 2
ORIC-114 for advanced lung or breast cancers with EGFR or HER2 changes

This early-phase study tests ORIC-114 to treat advanced solid tumors that have certain EGFR or HER2 genetic changes, often found in lung and breast cancers. It may help by targeting those specific cancer mutations, especially when standard treatments no longer work or aren’t tolerated.

Duarte, California

Hear when a new Objective Responsive Rate (ORR) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.