Immunotherapy with chemo for early triple-negative breast cancer
Treatments studied
Part of Cancer, Skin clinical trials.
This trial tests a combination of an immunotherapy drug (pembrolizumab) plus two chemotherapy drugs (carboplatin and paclitaxel) given before surgery for people with early-stage, triple-negative breast cancer. The goal is to see if this treatment helps shrink or eliminate the tumor before it's removed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older
- Your breast cancer is triple-negative (ER, PR, and HER2 are all negative or very low)
- Your cancer is stage 1, with the tumor size between T1b and T1c, and it has not spread to lymph nodes or other parts of the body
- You have not received immunotherapy or chemotherapy for this cancer before, and you have no recent live vaccines or active infections
- Your overall health is good (you can take care of yourself and are up and about most of the day)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests a combination of chemotherapy and immunotherapy given before surgery for triple-negative breast cancer. It aims to shrink the tumor and improve outcomes. The treatment is given intravenously.
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