Chemo, radiation and immunotherapy before surgery for stomach cancer with PALM
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests combining chemotherapy, radiation, and an immunotherapy drug (sintilimab) before surgery for advanced stomach cancer that has spread to lymph nodes near the aorta (called PALM). The goal is to see if this approach can shrink the tumor enough to allow complete removal.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have stomach or gastroesophageal junction adenocarcinoma that has spread only to para-aortic lymph nodes (PALM), with no spread to other organs.
- You have not received any prior cancer treatment (like chemotherapy, radiation, or immunotherapy).
- You are in good physical condition (ECOG score 0 or 1) and have adequate organ function (kidneys, liver, bone marrow).
- You are willing to use effective birth control during and for several months after treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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