Tislelizumab plus S-1 for esophageal cancer after surgery
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests a combination of the immunotherapy drug tislelizumab and the chemotherapy drug S-1 for people with a specific type of esophageal cancer that still has some cancer cells in the main tumor but no cancer in lymph nodes after surgery. The goal is to see if this treatment can help prevent the cancer from coming back.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have esophageal squamous cell cancer that was treated with immunotherapy and chemotherapy before surgery (no radiation planned during the study).
- After surgery, the main tumor still had some cancer cells (stage ypT1-4a) but no cancer in the lymph nodes (N0).
- You had surgery to completely remove the cancer (radical resection).
- You are able to perform your daily activities with little or no help (ECOG score 0 or 1).
- You have no signs of cancer recurrence or spread before starting treatment, and your organs are working well enough for chemotherapy and immunotherapy.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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