Letrozole for ectopic pregnancy treatment
Treatments studied
Part of Women’s health & pregnancy clinical trials.
This trial tests whether letrozole (a hormone-blocking pill) can treat an ectopic pregnancy safely and effectively, allowing you to keep your ability to have children. It is an alternative to methotrexate, and you'll be randomly assigned to one of the two treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been diagnosed with an ectopic pregnancy (pregnancy outside the womb) and want to preserve your ability to have children in the future.
- Your pregnancy hormone (hCG) level is 3000 mIU/mL or less, and the ultrasound shows the pregnancy is in a fallopian tube, is not actively growing, and is smaller than 3.5 cm.
- You have no major pain (less than 6 on a 0–10 pain scale) and are in stable health.
- You have not already had a big drop in hCG levels (more than 50% in 2 days), and you don't have certain liver or kidney problems, low blood counts, or an allergy to methotrexate or letrozole.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two medications (letrozole and methotrexate) to treat an ectopic pregnancy that has not ruptured. The goal is to see which drug is safer and more effective at resolving the pregnancy without surgery.
This study looks at using methotrexate (a medication) to treat ectopic pregnancy (a pregnancy outside the uterus) in women who have some health issues that might make the usual treatment riskier. It aims to see how well methotrexate works for them.
This study looks at how blood flow patterns around an ectopic pregnancy (pregnancy outside the uterus, in the fallopian tube) might predict whether medication or watchful waiting will work for you. Ectopic pregnancies cannot result in a baby and need treatment; this research aims to help doctors choose the best approach.
This trial compares two types of minimally invasive surgery for ectopic pregnancy to see which works better. Both procedures remove the fallopian tube and pregnancy without a large belly incision.
This trial tests a longer course of letrozole to help women with PCOS ovulate and get pregnant. The goal is to see if extended therapy works better than the standard treatment.
This trial compares two ways to prepare the uterus for a frozen embryo transfer: using the hormone letrozole or a standard artificial cycle. The goal is to see which approach works better for people with irregular periods.
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