Severe nasal polyps: links between symptoms, tissue, and blood
Part of Ear, nose & throat, Lungs & breathing clinical trials.
This study looks at people with severe nasal polyps that need surgery (ethmoidectomy) for the first time. Researchers want to understand the connection between your symptoms, nasal tissue, and blood tests.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- You have severe nasal polyps that did not get better with medication, and you are having surgery (ethmoidectomy) for the first time.
- You have not taken any biologic drugs (like Dupixent, Xolair, Nucala, or Fasenra) in the past or currently.
- You have not taken oral steroids (like prednisone) in the 4 weeks before surgery.
- You are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at different “immune inflammation patterns” in people with asthma and/or nasal polyps. It may help researchers better tailor future treatments by figuring out which patterns go with which symptoms.
This trial tests a more thorough sinus surgery combined with removing lymphoid tissue in the throat to see if it helps people with nasal polyps. Researchers want to know if this approach reduces inflammation and improves symptoms.
This trial tests an in-clinic (not hospital) endoscopic procedure to remove nasal polyps in people with chronic sinus inflammation, after usual medicines haven’t helped. It may help reduce nasal blockage and improve sinus symptoms, while comparing safety and outcomes after the procedure.
This trial compares three different biologic medications (injectable drugs) to see which one works best for people with chronic sinusitis and nasal polyps. If you have moderate to severe symptoms and are considering biologic therapy, this study might help find the best option for you.
This study examines tissue samples and inflammation patterns from people with chronic nasal polyps to better understand the condition. Researchers will take small biopsies to identify what drives nasal polyp growth, which may help develop better treatments in the future.
This study examines the type of inflammation in nasal polyps by collecting small tissue samples during surgery. It may help doctors better understand why some people develop nasal polyps and how to treat them more effectively.
Hear when a new Nasal Polyps trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.