Extending systemic therapy with local treatment for limited cancer growth
Part of Cancer clinical trials.
This trial tests whether adding local treatments like radiation or surgery to standard therapy can help control cancer that has started to grow in just a few spots. It is for people with certain advanced cancers that have 1 to 5 growing lesions that can be treated locally.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have stage IV cancer of the colon/rectum, kidney, breast, pancreas, bladder, prostate, or esophagus.
- You must have between 1 and 5 spots of cancer that have started growing, and each of these spots can be treated with radiation or other local therapy.
- You must be well enough to carry out daily activities (ECOG score 0-2).
- You must not have had more than 4 previous cancer treatments for metastatic disease.
- You must not have cancer spread to the lining of the brain, widespread cancer in the abdominal cavity, or fluid buildup around the lungs or belly.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether giving focused, high-dose radiation to spots where the cancer is growing can help control the disease while you stay on your current hormone therapy and/or CDK4/6 inhibitor. It is for people with ER+/HER2- breast cancer that has spread to a few places and is slowly starting to progress.
This trial compares two types of radiation for people whose cancer has spread to a few new spots while on or after treatment. It tests whether a precise, high-dose radiation approach (stereotactic) works better than the usual palliative radiation for controlling these growing spots.
This trial tests whether giving radiation to a few growing cancer spots while continuing your current treatment works better than switching to a new treatment right away. It's for people whose advanced liver cancer has only barely started to progress on their first therapy.
This trial tests whether continuing your current therapy after getting local treatment (like surgery or radiation) for a small area of cancer growth is safe and effective. It may help you keep the same treatment longer before switching to a new one.
This trial tests whether using local treatments (like targeted radiation or ablation) on a few new spots of cancer can help people whose cancer is otherwise stable on their current treatment. It enrolls people with various solid tumors, such as breast, gynecologic, head & neck, sarcoma, or other types.
This trial compares continuing drug therapy alone versus adding local treatments (surgery or radiation) for people with stage IV lung cancer that has responded to initial treatment but still has a few remaining spots (oligometastatic). The goal is to see if targeting those spots with local therapy helps control the cancer longer.
Hear when a new OligoProgressive Metastatic Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.