Combination therapy for relapsed Hodgkin lymphoma without transplant
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests a combination of two oral targeted drugs (chidamide and decitabine) plus an immunotherapy drug (anti-PD-1 antibody) for people with classical Hodgkin lymphoma that has not responded to at least two prior treatments and who cannot or choose not to have a stem cell transplant. The goal is to see if this three-drug combination can shrink tumors and help control the disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 75 years old
- You need to have classical Hodgkin lymphoma that has come back or not responded after at least two prior treatments
- You are not able to have a stem cell transplant, or you have chosen not to have one
- You should have a tumor that can be measured on a scan (at least 1 cm in size)
- You must be in generally good health (able to do day-to-day activities) and have adequate organ function
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a combination of three drugs (chidamide, decitabine, and an immunotherapy) for people with classical Hodgkin lymphoma that has come back or not responded to at least two prior treatments. It is for patients who cannot or choose not to have a stem cell transplant.
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