New drug combo for advanced Hodgkin lymphoma
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests a combination of three drugs (chidamide, decitabine, and an immunotherapy) for people with classical Hodgkin lymphoma that has come back or not responded to at least two prior treatments. It is for patients who cannot or choose not to have a stem cell transplant.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have classical Hodgkin lymphoma that has been confirmed by a biopsy.
- You have tried at least two previous cancer treatments and are not eligible for or have declined a stem cell transplant.
- You are in generally good health (able to do daily activities) and have adequate organ function.
- You have at least one tumor that can be measured (larger than 1 cm).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a combination of two oral targeted drugs (chidamide and decitabine) plus an immunotherapy drug (anti-PD-1 antibody) for people with classical Hodgkin lymphoma that has not responded to at least two prior treatments and who cannot or choose not to have a stem cell transplant. The goal is to see if this three-drug combination can shrink tumors and help control the disease.
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