Clin2
NCT06415487Possibly a fitRecruiting

Testing a new cell therapy for advanced EGFR-positive solid tumors

Locally Advanced Solid TumorMetastatic Solid Tumor

Treatments studied

Part of Cancer clinical trials.

This trial tests a new cell therapy called ACE2016 for people with advanced solid tumors that have EGFR on their surface. It may be an option if you have tried at least two other treatments (including a targeted therapy) and your cancer is still growing.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
30 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • Your cancer must be advanced (spread or cannot be removed by surgery) and express a protein called EGFR on its surface.
  • You must have tried at least two previous treatments, and one of them must be a targeted therapy.
  • You must have at least one tumor that can be measured with scans.
  • You must be feeling well enough to be up and about (ECOG score 0 or 1).
  • You must have normal heart, kidney, liver, and blood function, and your oxygen level must be 92% or higher on room air.
  • You cannot have had a certain type of cell therapy that targets EGFR before, and you cannot have active infections, untreated brain tumors, or a history of organ transplant or other cancers that are not cured.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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