New treatment for active ulcerative colitis
Treatments studied
Part of Digestive system clinical trials.
This trial tests a new treatment for people with ulcerative colitis (UC) whose disease is active despite taking only mesalamine or sulfasalazine. It aims to find a therapy that can reduce inflammation and improve symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have had ulcerative colitis (UC) for at least 3 months.
- Your colonoscopy showed at least 15 cm (about 6 inches) of colon is affected by UC.
- A recent stool test (calprotectin) shows a level above 200, meaning your UC is active.
- You are only taking mesalamine or sulfasalazine (not other UC medications).
- You are not using any rectal treatments (like enemas or suppositories) for UC.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a new oral medication for people with active ulcerative colitis that hasn't responded well to standard treatments. The goal is to see if the drug reduces inflammation and improves symptoms.
This trial tests new medicines for people with moderate to severe ulcerative colitis who haven't found relief with standard treatments. Participants will receive one of several investigational drugs (these are not yet approved and are being studied for safety and tolerability). The goal is to see if the drugs are safe and if they might help control symptoms.
This trial tests a new medicine to see if it's safe for people with moderate to severe ulcerative colitis. It also tests the medicine in healthy volunteers to check for side effects. If you have ulcerative colitis, this might offer a new treatment option.
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