Clin2
NCT06425926Possibly a fitRecruiting

Study of GIM-531 in advanced solid tumors

Melanoma Stage IVSolid Tumor

Treatments studied

Part of Cancer, Skin clinical trials.

This study tests a new oral drug, GIM-531, alone and in combination with an anti-PD-1 therapy for people with advanced solid tumors that have stopped responding to standard treatments. The goal is to see if it is safe and effective.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
117 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have an advanced solid tumor (cancer that has spread or cannot be removed) and standard treatments have stopped working or are not available.
  • You are able to do most daily activities (ECOG 0 or 1).
  • You must be willing to provide a fresh tumor biopsy or have one taken within the past year.
  • You must have measurable disease as seen on scans (per RECIST criteria).
  • If you have brain metastases, they must be treated and stable for at least 4 weeks, and you must be on a low or no steroid dose.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07612137Not yet recruiting· Phase 1/Phase 2
Study of IBI3005 combination therapy for advanced solid tumors

This trial tests a new drug called IBI3005, given with other treatments, for people with advanced solid tumors that cannot be removed by surgery or have spread. It may help shrink tumors or slow their growth.

Guangzhou, Guangdong
NCT06963281Recruiting· Phase 1
Study of an experimental drug for late-stage solid tumors

This trial tests an experimental drug called IBI3020 for people with advanced solid tumors that have not responded to standard treatments. It aims to see if the drug is safe and effective for these patients.

Phoenix, Arizona
NCT06028074Recruiting· Phase 1/Phase 2
Study of GIM-122 for advanced solid tumors

This trial tests a new drug, GIM-122, in people with advanced solid tumors that have stopped responding to or cannot tolerate standard PD-1/PD-L1 inhibitors. The goal is to see if GIM-122 is safe and tolerable.

Los Angeles, California
NCT05101070Recruiting· Phase 1/Phase 2
Study of an anti-cancer drug alone or with immunotherapy

This Phase 1/2 study tests a new cancer drug (S-531011) in people with advanced or metastatic solid tumors, either by itself or combined with an immunotherapy drug. It may help shrink tumors and learn how the treatment works, but it also requires extra procedures like repeat tumor biopsies and frequent monitoring.

Los Angeles, California
NCT06132217Not yet recruiting· Phase 1/Phase 2
Combination therapy for advanced solid tumors

This study tests a combination of two investigational drugs (Simmitinib and SG001) in people with advanced solid tumors that have not responded to standard treatment. The goal is to see if this combination can shrink tumors or slow their growth, and to find the best dose for further studies.

Beijing, Beijing Municipality
NCT06258304Recruiting· Phase 1
Testing a new immunotherapy for advanced solid tumors

This trial tests a new immunotherapy drug, GIGA-564, for people with advanced solid tumors that have not responded to or have returned after standard treatments. The goal is to see if the drug is safe and effective, and to find the best dose.

Bethesda, Maryland

Hear when a new Melanoma Stage IV trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.