Combination therapy for advanced solid tumors
Treatments studied
Part of Cancer clinical trials.
This study tests a combination of two investigational drugs (Simmitinib and SG001) in people with advanced solid tumors that have not responded to standard treatment. The goal is to see if this combination can shrink tumors or slow their growth, and to find the best dose for further studies.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have an advanced solid tumor (cancer) that cannot be removed by surgery or has spread to other parts of your body.
- Your cancer has worsened after standard treatment, or there is no standard treatment available for your cancer type.
- If you are in the expansion phase, you must be willing to provide a tissue sample (biopsy) to measure certain markers like PD-L1 or MSI/dMMR.
- You must have at least one measurable tumor, meaning it can be seen on scans and its size can be tracked.
- You need to have adequate kidney, liver, and bone marrow function, as shown by blood tests, and be able to perform daily activities independently.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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