Can some women safely skip radiation after breast cancer surgery?
Part of Cancer, Skin clinical trials.
This trial is for women 50 and older with early-stage, hormone-positive or HER2-positive breast cancer. It tests whether it is safe to skip radiation therapy after a lumpectomy if an MRI before surgery shows the breast tissue looks a certain way.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman aged 50 or older with early-stage breast cancer that is hormone receptor positive or HER2 positive.
- You have not had breast cancer or DCIS before, and you don't carry a known breast cancer gene mutation.
- You are planning to have breast-conserving surgery (lumpectomy), not a mastectomy.
- After surgery, the tumor must be no larger than 20 mm (about the size of a grape) and the margins (the healthy tissue around the tumor) must be clear.
- You agree to have a breast MRI before surgery, and you are willing to be in the study for 10 years of follow-up.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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