Radiation after lumpectomy for node-negative breast cancer
Part of Cancer, Skin clinical trials.
This trial studies whether a specific radiation approach after lumpectomy can be helpful for certain people with early breast cancer that did not spread to lymph nodes at diagnosis. It focuses on people who finish neoadjuvant (before-surgery) treatment and reach a full response on final pathology.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman, age 50 or older, with a new diagnosis of breast cancer
- Your initial tests showed no involved lymph nodes (based on ultrasound or MRI and/or needle biopsy)
- You received at least 8 weeks of chemotherapy before surgery (and if HER2-positive, you also received HER2-targeted therapy)
- A small marker clip was placed in the tumor area before/during chemotherapy while it was still visible
- You had lumpectomy (breast-conserving surgery) with lymph node staging (sentinel node biopsy or axillary node surgery)
- After surgery, your final pathology showed a complete response with no remaining invasive or in-situ cancer in the breast or lymph nodes (ypT0N0)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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