Immuno-chemo before surgery for thick or large stomach cancers
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests a combination of immunotherapy and chemotherapy given before surgery to shrink stomach cancers that are particularly thick or large. It aims to see if this approach can make these hard-to-treat tumors easier to remove and improve outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have stomach cancer that has not spread to other organs, and it is either a hard, thick-walled type (Type 4) or a large tumor bigger than 8 cm (large Type 3).
- You should be between 18 and 70 years old and in good enough health to get around (ECOG 0 or 1).
- Before starting, you need a surgery with a tiny camera to check that the cancer hasn't spread to the lining of your belly.
- Your blood counts and organ function (liver, kidneys, clotting) must be within a certain healthy range.
- You cannot have had any previous chemotherapy, radiation, or immunotherapy for this cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests whether adding an immunotherapy drug (tislelizumab) to standard chemotherapy before and after surgery can help treat stomach or gastroesophageal junction cancer. It is for people whose cancer has not spread to other organs and who are well enough to have surgery.
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