Clin2
NCT06453044Possibly a fitRecruiting

Study of two drugs for follicular lymphoma that came back

Recurrent Grade 1 Follicular LymphomaRecurrent Grade 2 Follicular LymphomaRecurrent Grade 3a Follicular LymphomaRefractory Grade 1 Follicular LymphomaRefractory Grade 2 Follicular LymphomaRefractory Grade 3a Follicular Lymphoma

Treatments studied

Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.

This study tests a combination of two targeted drugs (mosunetuzumab and polatuzumab vedotin) for people with follicular lymphoma that has come back or not responded to previous treatment. The goal is to see if this two-drug approach can help shrink tumors and control the disease.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
41 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have follicular lymphoma (grade 1, 2, or 3a) that has come back or not responded to at least one prior treatment.
  • You have measurable disease on a scan (for example, a lymph node at least 1.5 cm).
  • You are 18 or older and in fairly good health (able to do daily activities with some help if needed).
  • You have not had specific treatments like mosunetuzumab, polatuzumab vedotin, or a stem cell transplant in the recent past.
  • You have a recent tumor biopsy sample available or are willing to have one taken.
  • You are willing to use effective birth control if you could become pregnant or father a child.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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