Aspirin dose study to prevent high blood pressure in pregnancy
Treatments studied
Part of Heart & circulation, Women’s health & pregnancy clinical trials.
This trial compares two doses of aspirin to see which is better at preventing conditions like preeclampsia (a serious form of high blood pressure during pregnancy). You may qualify if you are in early pregnancy and have certain risk factors.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 14 years old and pregnant with a single baby or twins (up to 16 weeks 6 days).
- You have at least one high-risk condition (like prior preeclampsia, chronic high blood pressure, diabetes before pregnancy, kidney disease, autoimmune disease, or carrying twins) OR two moderate-risk conditions (like first pregnancy, obesity, age 35 or older, Black race, low income, IVF, or family history of preeclampsia).
- You are not currently taking aspirin, or you are taking it for a pregnancy-related reason and can start it within a certain time frame.
- You do not have allergies or medical problems that make aspirin unsafe (such as bleeding issues or certain stomach conditions).
- You are not planning to deliver at a hospital that cannot share your records.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two doses of aspirin (150 mg vs 100 mg) to see which is better at preventing preeclampsia, a serious pregnancy complication involving high blood pressure, in women who are obese and at higher risk. If you qualify, you would take one aspirin dose daily during pregnancy.
This trial compares two different doses of aspirin (a common safe medication) to see if one works better at preventing preeclampsia, a pregnancy complication, in women at higher risk. Taking part may help doctors find the best way to protect both you and your baby.
This study looks at whether taking aspirin for a longer or shorter time during pregnancy can better prevent preeclampsia, a serious condition with high blood pressure. It is for pregnant women already taking daily aspirin and found to be at high risk.
This study tests whether alerting doctors helps more pregnant people with increased risk for preeclampsia start taking low-dose aspirin to prevent it. If you're at higher risk, taking aspirin might help protect you and your baby.
This trial tests whether adding aspirin and hydroxychloroquine can lower the risk of preeclampsia during pregnancy in people considered high-risk. If you qualify, you may be assigned to take the study medicines to help protect you and the baby.
This study looks at how pregnant women at risk of pre-eclampsia process aspirin and how it affects their metabolism. Researchers will use blood and urine tests, along with body measurements and surveys, to learn more about how aspirin can help prevent pre-eclampsia.
Hear when a new Preeclampsia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.