Safety check for Dovprela in real-world use
Part of Infections clinical trials.
This study monitors how well the drug Dovprela (pretomanid) works and how safe it is when doctors prescribe it normally for drug-resistant tuberculosis. It gathers information from patients already taking the medication as part of their regular treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be prescribed Dovprela tablets by your doctor as part of your standard care.
- You must agree to let the study use your medical data by signing a privacy form.
- You cannot be allergic to pretomanid or any of the inactive ingredients in the tablet.
- You cannot have a medical reason that prevents you from also taking bedaquiline and linezolid (the two other medicines Dovprela is always given with).
- You must not have galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption (rare genetic problems).
- You cannot be pregnant or breastfeeding unless your doctor decides it is still safe.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies a specific drug combination (BPaLM) for adults with drug-resistant pulmonary (lung) tuberculosis. If you qualify, the goal is to see whether this treatment is effective and safe for your type of infection.
This trial tests a shorter treatment for drug-resistant tuberculosis (TB) using the medicine Pretomanid. It aims to find a more manageable cure for people whose TB does not respond to the standard first-line drug, rifampicin.
This trial tests a three-drug combination (bedaquiline, delamanid, and linezolid) to see if it's safe and works well for people with multi-drug resistant or rifampicin-resistant tuberculosis. It may offer a new treatment option if standard drugs aren't working.
This trial tests a new tablet called JDB0131 for people with tuberculosis (TB) that is resistant to the antibiotic rifampicin. The goal is to see if it can effectively treat this hard-to-treat form of TB.
This study tests if bedaquiline can prevent tuberculosis (TB) in people who have been in close contact with someone with active TB, including people living with HIV. If you qualify, you would take the study medicine and be monitored to see if it prevents you from developing TB.
This study tests a new tuberculosis drug called TBD09 combined with other TB medicines in people with newly diagnosed, drug-sensitive TB. The goal is to see if this combination works well and is safe.
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