Single blood thinner after shielded stent for brain aneurysm
Part of Brain & nervous system, Heart & circulation clinical trials.
This study is testing whether using only one blood-thinning medication (single antiplatelet therapy) after placing a special stent (Pipeline Flex with Shield) is safe and effective for treating unruptured brain aneurysms. It is for people who have already been on two blood thinners for a few days before the stent placement.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have an unruptured brain aneurysm (one that hasn't bled) and are getting a Pipeline Flex with Shield stent.
- The main artery in your brain that the stent will go into is at least 2.5 mm wide, not heavily calcified, and not very curved.
- You must have taken two blood-thinning medications (dual antiplatelet therapy) for at least 3 days before the stent procedure.
- Your aneurysm shape is not irregular (not fusiform, blister-like, or dissecting).
- You have not had a stroke or aneurysm rupture in the last 3 months.
- You do not have a known allergy to clopidogrel or heparin, and your platelet count is not too low.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests using a drug-coated stent (a small tube that helps keep the artery open and slowly releases medicine) along with a shorter course of blood-thinning medicines to prevent another stroke in people who have a narrowed vertebral artery in the neck that has already caused symptoms.
This trial is collecting information from people who already received a specific type of stent (Lattice Flow-Diverting Dense-Mesh Stent) to treat an unruptured brain aneurysm. The goal is to learn how well the stent works and improve future treatments.
This study compares two common blood-thinner combinations to see which one works better at preventing clots during stent placement for an unruptured brain aneurysm. It is designed for people whose bodies process these medications normally, with the goal of finding the safest and most effective option.
This study looks at whether taking just one blood-thinning medicine (instead of two) after a stent procedure helps prevent future heart problems while lowering the risk of bleeding. It's for people who recently had a heart attack or unstable chest pain and had a stent placed.
This trial tests a treatment called Pipeline Embolization (a thin tube placed in the artery) to fix brain aneurysms that haven't ruptured. It might help stop the aneurysm from growing or bursting.
This trial tests a medicine called tirofiban that helps prevent blood clots after a stent is placed to treat a burst brain aneurysm. The goal is to see if adding this medicine improves recovery and reduces the chance of another bleed.
Hear when a new Treatment trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.