Clin2
NCT06485336Possibly a fitRecruiting

Atorvastatin for prevention of chronic migraine

Chronic Migraine

Treatments studied

Part of Brain & nervous system clinical trials.

This trial tests whether the cholesterol drug atorvastatin can reduce the number of migraine days in people with chronic migraine (15 or more headache days per month, including at least 8 migraine days). If you have frequent migraines and haven't tried statins before, this study may offer a new preventive option.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
300 people
Ages
18 years to 65 years
Study type
Interventional

Who can take part

  • You are between 18 and 64 years old.
  • You have chronic migraine (at least 15 headache days per month, with at least 8 migraine days) for the last 3 months.
  • Your migraines started before age 50 and at least one year ago.
  • You are not using other migraine prevention medications during the study.
  • If you can become pregnant, you must use effective birth control and not be pregnant or planning pregnancy.
  • You have not taken statins before and do not have certain liver, kidney, or thyroid conditions.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06810505Recruiting· Phase 3
Oral atogepant for preventing migraines in teens

This trial tests an oral medication called atogepant to see if it can prevent migraines in teens aged 12–17. It aims to reduce how often migraines happen and track any side effects.

Huntsville, Alabama
NCT03972124Recruiting· Phase 2
Cannabis to prevent migraine attacks before they start

This Phase 2 trial tests whether using cannabis can prevent migraine attacks from happening. It specifically looks at people with chronic migraine who have tried and not benefited from other prevention medicines.

Calgary, Alberta
NCT07691164Not yet recruiting
Tracking thinking and quality of life during migraine prevention

This study looks at how preventive treatments for severe migraines, like botulinum toxin injections or anti-CGRP antibody infusions, may affect thinking and quality of life. If you have frequent migraines that don't respond to other treatments, you might be able to join.

Strasbourg
NCT05889624Recruiting
Study of treatments for childhood migraine headaches

This study looks at ways to help children and teens with migraine headaches by testing a care approach that includes access to evidence-based treatment. It may help if your child has frequent migraine headaches and is starting (or not already on) certain migraine-preventive medicines.

Birmingham, Alabama
NCT06248671Recruiting· Phase 2
Atorvastatin for preventing migraine attacks

This trial tests whether a daily dose of atorvastatin (a common cholesterol medicine) can prevent migraine attacks in people with episodic migraine. You would keep a headache diary and be randomly assigned to take atorvastatin or a placebo for about 3 months.

Bergen
NCT07071506Recruiting
New tools to track migraine prevention

This study tests new ways to monitor how well preventive migraine treatments are working. It is for people with chronic migraine who may be starting or already using preventive medications.

Aarhus C, Denmark

Hear when a new Chronic Migraine trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.