Cooling therapy with or without cilostazol to prevent nerve damage from paclitaxel
Treatments studied
Part of Cancer, Hormones & metabolism, Women’s health & pregnancy clinical trials.
This study tests whether cooling your hands and feet during chemotherapy, with or without the medicine cilostazol, can help prevent nerve damage (numbness, tingling, or pain) caused by the drug paclitaxel. It is for people with gynecologic cancers who are about to start or have just finished paclitaxel treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have uterine, ovarian, fallopian tube, primary peritoneal, cervical, or vulvar cancer and are scheduled for (or have recently completed) 6 to 9 cycles of paclitaxel with carboplatin or cisplatin
- You have not had paclitaxel before
- You do not have significant numbness or pain in your hands or feet that needs medication
- You do not have diabetes with a high A1c level (above 7.0)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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