Clin2
NCT06494371Possibly a fitRecruiting

Study of LCAR-HL30 for Hodgkin's and anaplastic large cell lymphoma

Hodgkin's LymphomaAnaplastic Large Cell Lymphoma

Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.

This trial tests a new treatment called LCAR-HL30 for people with Hodgkin's lymphoma or anaplastic large cell lymphoma that has come back or not responded to therapy. The treatment targets cells with a protein called CD30 to help your body fight the cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
32 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old.
  • You have Hodgkin's lymphoma or anaplastic large cell lymphoma with CD30 protein (confirmed by a lab test).
  • Your cancer has come back after treatment or did not respond to previous therapy.
  • You have at least one measurable tumor, and are expected to live at least 3 more months.
  • You have not had certain prior treatments (like CAR-T therapy or a stem cell transplant from a donor) within a specific time.
  • You are not pregnant and agree to use effective birth control during the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT02917083Recruiting· Phase 1
CD30 CAR T cell treatment for hard-to-treat lymphomas

This Phase 1 trial tests a new immune therapy made from your own immune cells (CAR T cells) for relapsed or refractory Hodgkin or non-Hodgkin lymphoma that has CD30 on the tumor. It aims to see if the treatment can shrink the lymphoma and find the safest dose.

Houston, Texas
NCT02259556Recruiting· Phase 1/Phase 2
CAR T treatment for CD30-positive lymphomas after standard therapies

This trial tests a lab-made immune cell therapy (CAR T) that targets CD30 on certain lymphoma cells. It may help people whose Hodgkin or non-Hodgkin lymphoma has come back or did not respond to usual treatments, including transplant and other medicines.

Beijing, Beijing Municipality
NCT07248163Recruiting
Universal CAR-T cell therapy for non-Hodgkin lymphoma

This trial tests a universal CAR-T cell therapy for patients with non-Hodgkin lymphoma whose cancer cells have CD19 on their surface. It might help if standard treatments have not worked.

Shanghai
NCT06617286Not yet recruiting· Phase 1/Phase 2
CD30-targeted cell therapy after stem cell transplant for Hodgkin lymphoma

This trial tests a new cell therapy (CD30 CAR T-cells) given after a stem cell transplant to treat Hodgkin lymphoma that has not responded well. It may help your body's immune cells fight the cancer more effectively.

Valhalla, New York
NCT07729397Not yet recruiting· Phase 1
CAR T-cell therapy for CD30-positive lymphoma

This trial tests a new treatment that uses your own immune cells, modified to find and attack cancer cells that have a protein called CD30 on them. It may be an option if your lymphoma has come back or hasn't improved with other treatments.

Houston, Texas
NCT04083495Recruiting· Phase 2
CAR T treatment for relapsed CD30-positive T-cell lymphoma

This trial tests a lab-made immune therapy (CAR T cells) for lymphoma that has come back or did not respond to treatment, specifically CD30-positive T-cell lymphoma. The goal is to shrink the cancer and help keep it under control after previous therapies, including people who have relapsed after stem cell transplant.

Chapel Hill, North Carolina

Hear when a new Anaplastic Large Cell Lymphoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.