Donor microbiome pills for steroid-resistant skin or colon side effects
Part of Digestive system, Immune system & allergy, Skin clinical trials.
This trial tests whether a pill made from healthy donor bacteria (MTP-101-C) can help patients whose immune-related skin rash or colon inflammation did not improve with steroids. It's for people who had these side effects after receiving immunotherapy for cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a skin rash covering more than 30% of your body or moderate-to-severe colitis that needed steroids but didn't get better.
- You are willing to swallow capsules and provide blood and stool samples.
- You can have any type of cancer (solid tumor or blood cancer) and have been treated with immunotherapy like PD-1 or CTLA-4 inhibitors.
- You are not pregnant, not breastfeeding, and agree to use birth control during the study and for 4 months after.
- You have not taken certain other immune-suppressing drugs (like dupilumab or infliximab) for this side effect.
- You are not on antibiotics or have an active infection that requires antibiotics.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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