Comparing two numbing medicines for painful back tooth
Part of Mouth & dental, Pain clinical trials.
This trial tests if a non-steroidal anti-inflammatory drug (diclofenac potassium) injected into the ligament around a painful lower molar works better than a standard local anesthetic (articaine) for numbing. It is for people with a specific type of severe, ongoing tooth pain (symptomatic irreversible pulpitis).
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are generally healthy (classified as ASA I or II).
- You have a lower back tooth with sharp pain that gets worse with cold but the nerve is still alive.
- You are not allergic to the numbing medicine or other NSAIDs like ibuprofen.
- You are not pregnant or nursing.
- You have not taken any pain relievers in the last 12 hours before treatment.
- The painful tooth does not have advanced gum disease or signs that the nerve has died.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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