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NCT06514651Likely a fitRecruiting

MAQ-001 for advanced solid tumors after PD-1/PD-L1 therapy

Advanced Solid Tumor

Treatments studied

Part of Cancer clinical trials.

This study tests a new experimental drug called MAQ-001 in people with advanced solid tumors or lymphomas that have already been treated with a PD-1/PD-L1 checkpoint inhibitor. The goal is to see if MAQ-001 can shrink or control the cancer when other treatments are no longer working.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
30 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • 18 years old or older
  • You have an advanced solid tumor or lymphoma that has already been approved for treatment with a PD-1 or PD-L1 drug (like Keytruda, Opdivo, Tecentriq, etc.) and you have no other standard treatment options available. If you have a rare tumor where PD-1 has shown benefit, you may also be considered.
  • You are in good enough health to be up and about (ECOG 0 or 1) – meaning you can do most daily activities on your own with little help.
  • You have at least one tumor that can be measured on a CT scan or MRI.
  • You have not had recent cancer therapy (chemotherapy, radiation, immunotherapy) within the last 3 weeks or less than 5 half-lives of the drug, whichever is shorter.
  • You are willing to use effective birth control during the study and for 4 months after treatment ends (if applicable), and you are not pregnant or breastfeeding.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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