Caffeine for preventing apnea in preterm babies in Zambia
Treatments studied
Part of Lungs & breathing clinical trials.
This trial tests whether giving caffeine citrate can help prevent breathing pauses (apnea) in preterm babies who are ready to stop their current caffeine treatment. It aims to see if a short course of caffeine can keep babies stable after they come off oxygen and are eating well.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your baby was born between 29 weeks and 33 weeks and 6 days of pregnancy, or weighs between 1.0 and 2.0 kilograms if the dates are uncertain.
- Your baby is currently getting caffeine (or a similar medicine) to help with breathing, and the doctor plans to stop it soon.
- Your baby has been off oxygen for more than 48 hours.
- Your baby is eating all of their meals (by mouth or feeding tube) and not needing IV fluids for nutrition.
- The baby’s doctor says your baby is stable and ready to stop caffeine.
- You (the parent or guardian) are 18 years old or older.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
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This study looks at whether giving caffeine to premature babies helps keep their hearts stable. It may help parents understand if caffeine treatment is safe for their baby's heart.
This study uses EEG brain scans to find the best time to stop caffeine treatment in premature babies. Caffeine is given to help with breathing, and the goal is to see if brain activity can guide when to safely stop it.
This study tests if giving an extra dose of caffeine (a medicine that helps premature babies breathe) right before removing the breathing tube can make the transition easier. It is for very premature babies who have been on a ventilator for at least two days and are ready for their first try at breathing on their own.
This study looks at how caffeine is absorbed and transferred to a baby during pregnancy in women at risk of early delivery. Researchers hope to understand safe caffeine use in this situation and potentially help prevent complications.
This study looks at a new, gentler way to measure caffeine levels in preterm babies using a very small blood sample. The goal is to understand how caffeine moves in your baby's body so doctors can give the right dose with fewer needle sticks.
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