Caffeine for premature babies' breathing and health
Treatments studied
Part of Lungs & breathing, Women’s health & pregnancy clinical trials.
This trial tests whether giving caffeine citrate early to very premature babies (born before 32 weeks) improves their breathing and long-term health. It aims to find the best way to use this common medicine to help your baby grow and develop.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your baby was born before 32 weeks of pregnancy.
- Your baby is less than 72 hours old at the time of screening.
- Your baby's doctor has decided to start caffeine treatment (for breathing pauses, to help come off a breathing tube, or for other benefits).
- Your baby has not already had caffeine or similar medications.
- Your baby does not have a major birth defect or a known genetic syndrome.
- Your baby is not expected to die within the next 24 hours, and intensive care is being provided.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests whether giving caffeine citrate can help prevent breathing pauses (apnea) in preterm babies who are ready to stop their current caffeine treatment. It aims to see if a short course of caffeine can keep babies stable after they come off oxygen and are eating well.
This study looks at whether giving caffeine to premature babies helps keep their hearts stable. It may help parents understand if caffeine treatment is safe for their baby's heart.
This study uses EEG brain scans to find the best time to stop caffeine treatment in premature babies. Caffeine is given to help with breathing, and the goal is to see if brain activity can guide when to safely stop it.
This study looks at how caffeine is absorbed and transferred to a baby during pregnancy in women at risk of early delivery. Researchers hope to understand safe caffeine use in this situation and potentially help prevent complications.
This study tests if giving an extra dose of caffeine (a medicine that helps premature babies breathe) right before removing the breathing tube can make the transition easier. It is for very premature babies who have been on a ventilator for at least two days and are ready for their first try at breathing on their own.
This study looks at a new, gentler way to measure caffeine levels in preterm babies using a very small blood sample. The goal is to understand how caffeine moves in your baby's body so doctors can give the right dose with fewer needle sticks.
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