Study of bacterial overgrowth in patients with abdominal bloating
Treatments studied
Part of Digestive system clinical trials.
This trial looks at whether an overgrowth of bacteria in the small intestine causes bloating. It tests how well treatment works for people with functional bloating (bloating without a clear cause) who also have this bacterial overgrowth.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 60 years old.
- Your main symptom is bloating or a feeling of fullness in the belly, and this is more bothersome than any other stomach issue.
- You have not taken antibiotics or probiotics (good bacteria supplements) in the last 2 weeks.
- You have not taken certain stomach medicines (like antispasmodics, motility aids, or anti-gas drugs) in the last week.
- You have not had cancer or abdominal surgery in the past.
- You do not have food allergies, lactose intolerance, or serious diseases outside the digestive system (like kidney disease, Parkinson's, depression, etc.).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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Other trials that look related to this one.
This study tests whether the antibiotic rifaximin can relieve bloating in people with small intestinal bacterial overgrowth (SIBO). If you have chronic bloating and a positive SIBO breath test, this trial may be a good fit.
This study looks at whether certain bacteria in the small intestine cause abdominal bloating and distension. It aims to help understand this common problem and find better ways to treat it.
This study tests whether rifaximin, an antibiotic that works in the gut, can reduce bloating in people with irritable bowel syndrome, constipation, or functional bloating. Rifaximin may help by changing the balance of bacteria in your intestines.
This study tests how Rifaximin (a medicine for SIBO) affects the bacteria and other substances in your gut. You'll swallow a small capsule that collects samples as it travels through your digestive system, so researchers can see how your gut changes during treatment.
This trial tests whether adding a probiotic supplement to standard antibiotic therapy (rifaximin) works better than the antibiotic alone for treating small intestinal bacterial overgrowth (SIBO) in people with irritable bowel syndrome (IBS). If you have IBS and SIBO, this study could help find a more effective treatment.
This study uses a tiny capsule to collect samples from your small intestine to learn about gut bacteria in people with IBS or other functional gut disorders. It could help researchers understand what causes digestive symptoms.
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