Rifaximin for bloating in functional bowel disorders
Treatments studied
Part of Digestive system clinical trials.
This trial tests a medication called rifaximin (an antibiotic that works in the gut) to see if it reduces bloating in people with functional bowel disorders like IBS or chronic constipation. If you have stubborn bloating despite treatment, this could be a new option to help you feel better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 80 years old.
- You have a diagnosis of irritable bowel syndrome, chronic constipation, or bloating without a clear cause (Rome IV criteria).
- Your bloating is bothersome (at least a 3 on a 0–6 scale) even after treating constipation.
- You have not had major stomach or bowel surgery (appendix or gallbladder removal is okay).
- You do not have inflammatory bowel disease or other gut inflammation.
- You can stop certain medications that affect gut bacteria or bloating (like antibiotics, acid reducers, probiotics, NSAIDs, metformin, simethicone, or anti-diarrheal drugs) during the trial.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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