Clin2
NCT06524778Possibly a fitNot yet recruiting

Single high-dose brachytherapy for giant osteosarcoma masses

Osteosarcoma

Part of Cancer clinical trials.

This study tests a radiation treatment called brachytherapy, which delivers a high dose of radiation directly to the tumor. It is for people with osteosarcoma that cannot be removed by surgery and has not responded to other treatments. The goal is to shrink the tumor and control symptoms.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
16 people
Ages
12 years to 70 years
Study type
Interventional

Who can take part

  • You have been diagnosed with osteosarcoma, a type of bone cancer.
  • You are between 12 and 70 years old.
  • Your tumor cannot be removed with surgery, and standard treatments like chemo, targeted therapy, or immunotherapy have not worked.
  • Your tumor measures more than 5 centimeters (about 2 inches) across.
  • You have not had radiation to the tumor area before, and you are not pregnant or breastfeeding.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06114225Recruiting· Phase 2
Immunotherapy and radiation before lung surgery for osteosarcoma

This trial tests a combination of immunotherapy and targeted radiation before surgery for osteosarcoma that has spread to the lungs. It aims to see if this approach can help shrink or control the lung tumors and make surgery more effective.

Shanghai, Shanghai Municipality
NCT06492954Recruiting· Phase 1
Testing atezolizumab with radiation and surgery for lung-only osteosarcoma

This trial tests whether combining an immunotherapy drug (atezolizumab) with focused radiation and surgery can help people whose osteosarcoma has come back only in the lungs. It aims to see if this approach is safe and may improve outcomes.

Atlanta, Georgia
NCT06384404Recruiting
Surgery First for Osteosarcoma of the Arm or Leg

This trial tests removing the tumor with surgery first, then following up with chemotherapy. It's for people with a new, high-grade osteosarcoma in an arm or leg that hasn't spread.

The Bronx, New York
NCT06650514Recruiting· Phase 2
OMO-103 for advanced osteosarcoma

This trial tests a new drug called OMO-103, which targets a protein called Myc that helps cancer cells grow. It is for people with advanced osteosarcoma (bone cancer) that has worsened after standard chemotherapy. The drug is given intravenously (through a vein), and the study will check if it is safe and shrinks tumors.

Barcelona
NCT05830123Recruiting· Phase 2
Test drug HS-20093 for osteosarcoma after earlier treatment

This Phase 2 trial studies HS-20093 in adults with osteosarcoma or other sarcomas that came back or did not respond to standard treatment. It aims to see how well the drug works and whether it is safe for people whose cancer has progressed.

Beijing
NCT06778603Recruiting· Phase 1/Phase 2
Using B7-H3 imaging to guide osteosarcoma surgery

This trial tests a special dye that targets B7-H3, a protein found on osteosarcoma cells. Before your surgery, the dye is injected and helps surgeons see tumor edges more clearly, so they can remove all of the cancer while saving healthy tissue.

Beijing, Beijing Municipality

Hear when a new Osteosarcoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.