Botox before radiation for head and neck cancer
Treatments studied
Part of Cancer clinical trials.
This trial tests whether injecting botulinum toxin (Botox) before radiation therapy can help protect your salivary glands and reduce dry mouth, a common side effect of radiation for head and neck cancer. If you're newly diagnosed with advanced head and neck cancer and are about to start radiation, this could be an option to explore.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a new diagnosis of head and neck cancer (specifically mucosal squamous cell carcinoma) at stage III or IVa.
- You must be scheduled to receive radiation therapy (with or without chemotherapy) as part of your treatment.
- You must not have had radiation therapy to the head or neck before.
- You must not have received prior treatment for head and neck cancer.
- You must not already have chronic dry mouth (xerostomia), and you must not have had major salivary gland surgery or radioactive iodine therapy in the past.
- You must not be allergic to botulinum toxin type A (Botox).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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