Clin2
NCT06538012Possibly a fitRecruiting

Tumor immune cells plus pembrolizumab for advanced lung cancer

Lung CancerLung Cancer MetastaticLung Cancer, Non-small CellLung Cancer Recurrent

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This trial tests a new approach: taking immune cells from your own tumor (TILs), growing them in the lab, then giving them back to you along with the immunotherapy drug pembrolizumab. It is for people with advanced lung cancer who have run out of standard options.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
85 people
Ages
16 years to 90 years
Study type
Interventional

Who can take part

  • You are between 16 and 90 years old.
  • You have been diagnosed with lung cancer that has spread or come back, and standard treatments have stopped working or are not available.
  • You have at least one tumor that can be taken out with surgery or a biopsy, or fluid around your lung that can be drained to collect special immune cells called TILs.
  • Your general health is good enough to undergo a procedure (like a biopsy) and you are expected to live at least 3 more months.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07222566Recruiting· Phase 3
New drug plus chemotherapy for advanced lung cancer

This trial tests a new study drug called PF-08634404 combined with standard chemotherapy for people with advanced lung cancer that has not been treated before. It aims to see if this combination works better than chemotherapy alone.

Bullhead City, Arizona
NCT03356808Not yet recruiting· Phase 1/Phase 2
Immune cell therapy for advanced lung cancer

This trial tests a personalized immune cell therapy for advanced or relapsed lung cancer. Doctors take your blood, create special T cells that target unique proteins on your cancer, and give them back to you to try to fight the tumor.

Shenzhen, Guangdong
NCT06640582Recruiting· Phase 1/Phase 2
TIL therapy with pembrolizumab for advanced brain cancer

This trial tests a new treatment for advanced brain cancers like glioma and meningioma. It combines your own immune cells (tumor-infiltrating lymphocytes or TILs) with an immunotherapy drug (pembrolizumab) to help your body fight the tumor. It's for people who have tried other treatments without success or have no standard options left.

Beijing, Beijing Municipality
NCT06532799Recruiting· Phase 1/Phase 2
TIL therapy with pembrolizumab for advanced stomach and esophageal cancer

This trial tests a combination of immune cells from your tumor (TILs) and an immunotherapy drug (pembrolizumab) for stomach or esophageal cancer that has spread or returned after other treatments. It may help if standard options have failed.

Beijing, Beijing Municipality
NCT06532812Recruiting· Phase 1/Phase 2
TIL therapy plus immunotherapy for advanced breast cancer

This trial tests a personalized therapy using your own immune cells (TILs) combined with immunotherapy to fight advanced breast cancer that has not responded to other treatments. It may help if you have a tumor that can be biopsied and you are generally healthy enough for the procedures.

Beijing, Beijing Municipality
NCT06045767Not yet recruiting· Phase 2
Pembrolizumab for advanced lung cancer: T-cell test

This trial tests a drug called pembrolizumab (Keytruda) in people with advanced non-small cell lung cancer who haven't received treatment for metastatic disease. Researchers will also study your T-cells (a type of immune cell) to see if they can predict how well the drug works.

Hear when a new Lung cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.