TIL therapy with pembrolizumab for advanced brain cancer
Treatments studied
Part of Brain & nervous system, Cancer clinical trials.
This trial tests a new treatment for advanced brain cancers like glioma and meningioma. It combines your own immune cells (tumor-infiltrating lymphocytes or TILs) with an immunotherapy drug (pembrolizumab) to help your body fight the tumor. It's for people who have tried other treatments without success or have no standard options left.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 16 to 90 years old.
- You have a type of brain cancer called glioma or meningioma that has come back, spread, or not responded to treatment.
- You are healthy enough for surgery to remove a tumor sample, and your expected survival is more than 3 months.
- You can perform daily activities with some help (Karnofsky score 60% or higher, or ECOG 0-2).
- Your blood counts and organ function are within certain limits (checked within the week before starting).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This trial tests a type of immune cell treatment called TIL (tumor-infiltrating lymphocytes) in people with advanced solid cancers. It may help your immune system better recognize and attack tumors, especially if standard treatments have not worked.
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