Clin2
NCT06543407Possibly a fitRecruiting

Safer smoking options for people with mental illness

Tobacco Dependence

Part of Mental health clinical trials.

This study offers a way to reduce harm from smoking for people with mental health conditions who are not ready to quit. It tests if switching to a less harmful product can help improve health without requiring you to stop smoking completely.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
250 people
Ages
21 years and older
Study type
Interventional

Who can take part

  • You have a mental health condition like schizophrenia, bipolar disorder, major depression, PTSD, or an anxiety disorder.
  • You are 21 years or older.
  • You smoke at least 10 cigarettes every day.
  • You have tried to quit smoking at least once in the last 5 years using medicine or counseling.
  • You are not currently interested in quitting smoking.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05815199Recruiting
E-cigarettes to help smokers with serious mental illness cut down

This study tests whether e-cigarettes can help people who smoke a lot reduce cigarette use (without requiring them to quit completely). It is designed for adults with serious mental illness and focuses on harm reduction and follow-up over time.

New York, New York
NCT06373679Recruiting
Switch or Quit: A study for smokers who want to quit

This study helps adults 21 and older who have tried to quit smoking with a stop-smoking medication. You may be able to join if you want to try quitting again or want to reduce harm from tobacco.

Charleston, South Carolina
NCT06922617Recruiting
E-cigarettes vs. Nicotine Replacement for Smoking in Substance Use Treatment

This study compares e-cigarettes to nicotine replacement therapy (like patches or gum) to help people who are in treatment for substance use disorder (like drugs or alcohol) quit or reduce smoking. It aims to find a safer way to cut back on cigarettes.

Charleston, South Carolina
NCT06372899Recruiting
Switching to E-cigarettes or Nicotine Pouches for Smokers

This study tests whether switching to e-cigarettes or nicotine pouches can help smokers who have tried many times to quit. If you are a heavy smoker (at least 5 cigarettes a day) and have failed to quit before, this trial may offer a new way to reduce harm from smoking.

Philadelphia, Pennsylvania
NCT06944847Recruiting
Vaping and smoking study for people with schizophrenia

This study looks at habits of vaping and smoking in people with schizophrenia. It may help researchers understand how to better support people who want to reduce or quit nicotine use.

Buffalo, New York
NCT05703672Recruiting· Phase 3
Switching smokers to e-cigarettes who do not want to quit

This study tests whether switching from regular cigarettes to e-cigarettes helps smokers who are not interested in quitting. You would also be offered varenicline and regular check-ins to compare outcomes over time.

Kansas City, Missouri

Hear when a new Tobacco Dependence trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.