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NCT06547333Possibly a fitNot yet recruiting

Study of CM310 for moderate to severe chronic obstructive pulmonary disease (COPD)

Chronic Obstructive Pulmonary Disease

Part of Lungs & breathing clinical trials.

This study tests a new medication called CM310 for people with moderate to severe COPD who have frequent flare-ups and a certain type of inflammation. The goal is to see if CM310 can reduce these flare-ups and improve breathing.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
884 people
Ages
40 years to 85 years
Study type
Interventional

Who can take part

  • You are between 40 and 85 years old.
  • You have had COPD for at least 1 year and have moderate to severe COPD.
  • You have had at least 2 moderate or 1 severe COPD flare-up in the past year, and you were taking maintenance inhalers when they happened.
  • You have been on triple inhaler therapy (ICS, LABA, LAMA) for at least 3 months, or double therapy if you can't use ICS.
  • You have chronic bronchitis symptoms (cough and phlegm) for at least 3 months in the past year.
  • You have a certain level of blood eosinophils (a type of white blood cell) at the screening visit.
  • You have not been diagnosed with asthma.
  • You have not used certain biologic medications or had certain infections or conditions in the recent past.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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