CM310 for moderate to severe asthma despite current inhalers
Part of Lungs & breathing clinical trials.
This study tests CM310 to see if it can improve asthma in people with moderate to severe asthma who are still having uncontrolled symptoms and severe flare-ups despite regular inhaler treatment. You may be eligible if your lung function and asthma control tests fit the study limits and you’ve had a recent severe exacerbation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You can understand the study and sign the consent form yourself (or with a legally acceptable process).
- You are between 12 and 75 years old and weigh at least 40 kg.
- You have had asthma for at least 1 year, and your test results match GINA 2022 criteria.
- Your lung function is reduced at screening (FEV1 ≤ 80% of predicted), and you show bronchodilator response (bigger improvement after a rescue inhaler).
- Despite using medium-to-high dose inhaled steroid plus other controller medicine for at least 3 months (stable for at least 1 month), your asthma control scores are still high (ACQ-5 ≥ 1.5).
- You’ve had at least one severe asthma flare-up in the past 12 months, but none in the last month.
- If you could become pregnant (or have a partner who could), you agree to highly effective birth control starting now and for 3 months after the last study dose.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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